Intracellular neutralisation of rotavirus by VP6-specific IgG

Rotavirus is a major cause of gastroenteritis in children, with infection typically inducing high levels of protective antibodies. Antibodies targeting the middle capsid protein VP6 are particularly abundant, and as VP6 is only exposed inside cells, neutralisation must be post-entry. However, while...

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Udgivet i:PLoS Pathog
Main Authors: Caddy, Sarah L., Vaysburd, Marina, Wing, Mark, Foss, Stian, Andersen, Jan Terje, O‘Connell, Kevin, Mayes, Keith, Higginson, Katie, Iturriza-Gómara, Miren, Desselberger, Ulrich, James, Leo C.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428215/
https://ncbi.nlm.nih.gov/pubmed/32750093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008732
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