Cellular Senescence Is Immunogenic and Promotes Antitumor Immunity

Cellular senescence is a stress response that activates innate immune cells, but little is known about its interplay with the adaptive immune system. Here, we show that senescent cells combine several features that render them highly efficient in activating dendritic cells (DC) and antigen-specific...

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Detalles Bibliográficos
Publicado en:Cancer Discov
Autores principales: Marin, Ines, Boix, Olga, Garcia-Garijo, Andrea, Sirois, Isabelle, Caballe, Adrià, Zarzuela, Eduardo, Ruano, Irene, Attolini, Camille Stephan-Otto, Prats, Neus, López-Domínguez, José A, Kovatcheva, Marta, Garralda, Elena, Muñoz, Javier, Caron, Etienne, Abad, María, Gros, Alena, Pietrocola, Federico, Serrano, Manuel
Formato: Artigo
Lenguaje:Inglês
Publicado: American Association for Cancer Research 2023
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614152/
https://ncbi.nlm.nih.gov/pubmed/36302218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-22-0523
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