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Determinants for Neoantigen Identification
All tumors accumulate genetic alterations, some of which can give rise to mutated, non-self peptides presented by human leukocyte antigen (HLA) molecules and elicit T-cell responses. These immunogenic mutated peptides, or neoantigens, are foreign in nature and display exquisite tumor specificity. Th...
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| Pubblicato in: | Front Immunol |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6601353/ https://ncbi.nlm.nih.gov/pubmed/31293573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01392 |
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