Cellular Senescence Is Immunogenic and Promotes Antitumor Immunity

Cellular senescence is a stress response that activates innate immune cells, but little is known about its interplay with the adaptive immune system. Here, we show that senescent cells combine several features that render them highly efficient in activating dendritic cells (DC) and antigen-specific...

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Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Marin, Ines, Boix, Olga, Garcia-Garijo, Andrea, Sirois, Isabelle, Caballe, Adrià, Zarzuela, Eduardo, Ruano, Irene, Attolini, Camille Stephan-Otto, Prats, Neus, López-Domínguez, José A, Kovatcheva, Marta, Garralda, Elena, Muñoz, Javier, Caron, Etienne, Abad, María, Gros, Alena, Pietrocola, Federico, Serrano, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for Cancer Research 2023
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614152/
https://ncbi.nlm.nih.gov/pubmed/36302218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-22-0523
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