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Diene Incorporation by a Dehydratase Domain Variant in Modular Polyketide Synthases
Modular polyketide synthases (PKSs) are biosynthetic assembly lines that construct structurally diverse natural products with wide-ranging applications in medicine and agriculture. Various mechanisms contribute to structural diversification during PKS-mediated chain assembly, including dehydratase (...
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| Publié dans: | Nat Chem Biol |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2022
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7613849/ https://ncbi.nlm.nih.gov/pubmed/36109649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-022-01127-y |
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