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Short peptide pharmacophores developed from protein phosphatase-1 disrupting peptides (PDPs)
PP1 is a major phosphoserine/threonine-specific phosphatase that is involved in diseases such as heart insufficiency and diabetes. PP1-disrupting peptides (PDPs) are selective modulators of PP1 activity that release its catalytic subunit, which then dephosphorylates nearby substrates. Recently, PDPs...
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| Publicado en: | Bioorg Med Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2022
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7613447/ https://ncbi.nlm.nih.gov/pubmed/35525109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2022.116785 |
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