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Interrogating PP1 Activity in the MAPK Pathway with Optimized PP1‐Disrupting Peptides
Protein phosphatase‐1 (PP1)‐disrupting peptides (PDPs) are selective chemical modulators of PP1 that liberate the active PP1 catalytic subunit from regulatory proteins; thus allowing the dephosphorylation of nearby substrates. We have optimized the original cell‐active PDP3 for enhanced stability, a...
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| Publicat a: | Chembiochem |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6471087/ https://ncbi.nlm.nih.gov/pubmed/30338897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201800541 |
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