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Development of a Photoactivatable Protein Phosphatase-1-Disrupting Peptide

[Image: see text] We describe here the development of a photoreleasable version of a protein phosphatase-1 (PP1)-disrupting peptide (PDP-Nal) that triggers protein phosphatase-1 activity. PDP-Nal is a 23 mer that binds to PP1 through several interactions. It was photocaged on a tyrosine residue, whi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Org Chem
Egile Nagusiak: Trebacz, Malgorzata, Wang, Yansong, Makotta, Leslie, Henschke, Lars, Köhn, Maja
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2019
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7011174/
https://ncbi.nlm.nih.gov/pubmed/31841001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.9b02548
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