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Development of a Photoactivatable Protein Phosphatase-1-Disrupting Peptide
[Image: see text] We describe here the development of a photoreleasable version of a protein phosphatase-1 (PP1)-disrupting peptide (PDP-Nal) that triggers protein phosphatase-1 activity. PDP-Nal is a 23 mer that binds to PP1 through several interactions. It was photocaged on a tyrosine residue, whi...
Guardat en:
| Publicat a: | J Org Chem |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Chemical
Society
2019
|
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7011174/ https://ncbi.nlm.nih.gov/pubmed/31841001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.9b02548 |
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