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Effects of stably incorporated iron on protein phosphatase‐1 structure and activity

Protein phosphatase‐1 (PP1) drives a large amount of phosphoSer/Thr protein dephosphorylations in eukaryotes to counteract multiple kinases in signaling pathways. The phosphatase requires divalent metal cations for catalytic activity and contains iron naturally. Iron has been suggested to have an in...

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Detalhes bibliográficos
Publicado no:FEBS Lett
Main Authors: Salvi, Francesca, Trebacz, Malgorzata, Kokot, Thomas, Hoermann, Bernhard, Rios, Pablo, Barabas, Orsolya, Kӧhn, Maja
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587554/
https://ncbi.nlm.nih.gov/pubmed/30403291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13284
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