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Mutational Analysis of a Conserved Glutamate Reveals Unique Mechanistic and Structural Features of the Phosphatase PRL-3

[Image: see text] Phosphatase of regenerating liver (PRL)-3 (PTP4A3) has gained much attention in cancer research due to its involvement in tumor promoting and metastatic processes. It belongs to the protein tyrosine phosphatase (PTP) superfamily and is thought to follow the catalytic mechanism shar...

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Vydáno v:ACS Omega
Hlavní autoři: Hoeger, Birgit, Rios, Pablo, Berteotti, Anna, Hoermann, Bernhard, Duan, Guangyou, Köhn, Maja
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2017
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044973/
https://ncbi.nlm.nih.gov/pubmed/30023603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b01208
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