Conformation space of a heterodimeric ABC exporter under turnover conditions

Cryo-electron microscopy (cryo-EM) has the capacity to capture molecular machines in action(1–3). ATP-binding cassette (ABC) exporters are highly dynamic membrane proteins that extrude a wide range of substances from the cytosol(4–6) and thereby contribute to essential cellular processes, adaptive i...

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Foilsithe in:Nature
Main Authors: Hofmann, Susanne, Januliene, Dovile, Mehdipour, Ahmad R., Thomas, Christoph, Stefan, Erich, Brüchert, Stefan, Kuhn, Benedikt T., Geertsma, Eric R., Hummer, Gerhard, Tampé, Robert, Moeller, Arne
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2019
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612745/
https://ncbi.nlm.nih.gov/pubmed/31316210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1391-0
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