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Mechanistic determinants of the directionality and energetics of active export by a heterodimeric ABC transporter
The ATP-binding cassette (ABC) transporter associated with antigen processing (TAP) participates in immune surveillance by moving proteasomal products into the endoplasmic reticulum (ER) lumen for major histocompatibility complex class I loading and cell surface presentation to cytotoxic T cells. He...
Enregistré dans:
| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Pub. Group
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4242082/ https://ncbi.nlm.nih.gov/pubmed/25377891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6419 |
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