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De novo macrocyclic peptides dissect energy coupling of a heterodimeric ABC transporter by multimode allosteric inhibition

ATP-binding cassette (ABC) transporters constitute the largest family of primary active transporters involved in a multitude of physiological processes and human diseases. Despite considerable efforts, it remains unclear how ABC transporters harness the chemical energy of ATP to drive substrate tran...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Stefan, Erich, Obexer, Richard, Hofmann, Susanne, Vu Huu, Khanh, Huang, Yichao, Morgner, Nina, Suga, Hiroaki, Tampé, Robert
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8116058/
https://ncbi.nlm.nih.gov/pubmed/33929325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.67732
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