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Subnanometer resolution cryo-EM structure of a nucleotide free heterodimeric ABC exporter
ATP-binding cassette (ABC) transporters translocate substrates across cell membranes, using energy harnessed from ATP binding and hydrolysis at their nucleotide binding domains (NBDs)(1,2). ABC exporters are present in both prokaryotes and eukaryotes with examples implicated in multidrug resistance...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4372080/ https://ncbi.nlm.nih.gov/pubmed/25363761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13872 |
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