Subnanometer resolution cryo-EM structure of a nucleotide free heterodimeric ABC exporter

ATP-binding cassette (ABC) transporters translocate substrates across cell membranes, using energy harnessed from ATP binding and hydrolysis at their nucleotide binding domains (NBDs)(1,2). ABC exporters are present in both prokaryotes and eukaryotes with examples implicated in multidrug resistance...

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Bibliografiska uppgifter
I publikationen:Nature
Huvudupphovsmän: Kim, JungMin, Wu, Shenping, Tomasiak, Thomas, Mergel, Claudia, Winter, Michael B., Stiller, Sebastian B., Robles-Colmanares, Yaneth, Stroud, Robert M., Tampé, Robert, Craik, Charles S., Cheng, Yifan
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372080/
https://ncbi.nlm.nih.gov/pubmed/25363761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13872
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