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Subnanometer resolution cryo-EM structure of a nucleotide free heterodimeric ABC exporter

ATP-binding cassette (ABC) transporters translocate substrates across cell membranes, using energy harnessed from ATP binding and hydrolysis at their nucleotide binding domains (NBDs)(1,2). ABC exporters are present in both prokaryotes and eukaryotes with examples implicated in multidrug resistance...

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Bibliografiske detaljer
Udgivet i:Nature
Main Authors: Kim, JungMin, Wu, Shenping, Tomasiak, Thomas, Mergel, Claudia, Winter, Michael B., Stiller, Sebastian B., Robles-Colmanares, Yaneth, Stroud, Robert M., Tampé, Robert, Craik, Charles S., Cheng, Yifan
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372080/
https://ncbi.nlm.nih.gov/pubmed/25363761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13872
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