Exploring conformational equilibria of a heterodimeric ABC transporter

ABC exporters pump substrates across the membrane by coupling ATP-driven movements of nucleotide binding domains (NBDs) to the transmembrane domains (TMDs), which switch between inward- and outward-facing (IF, OF) orientations. DEER measurements on the heterodimeric ABC exporter TM287/288 from Therm...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Timachi, M Hadi, Hutter, Cedric AJ, Hohl, Michael, Assafa, Tufa, Böhm, Simon, Mittal, Anshumali, Seeger, Markus A, Bordignon, Enrica
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Biophysics and Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216877/
https://ncbi.nlm.nih.gov/pubmed/28051765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.20236
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