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Exploring conformational equilibria of a heterodimeric ABC transporter
ABC exporters pump substrates across the membrane by coupling ATP-driven movements of nucleotide binding domains (NBDs) to the transmembrane domains (TMDs), which switch between inward- and outward-facing (IF, OF) orientations. DEER measurements on the heterodimeric ABC exporter TM287/288 from Therm...
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| Veröffentlicht in: | eLife |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5216877/ https://ncbi.nlm.nih.gov/pubmed/28051765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.20236 |
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