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Asymmetry in the Homodimeric ABC Transporter MsbA Recognized by a DARPin
ABC transporters harness the energy from ATP binding and hydrolysis to translocate substrates across the membrane. Binding of two ATP molecules at the nucleotide binding domains (NBDs) leads to the formation of an outward-facing state. The conformational changes required to reset the transporter to...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3370220/ https://ncbi.nlm.nih.gov/pubmed/22523072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.359794 |
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