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Flexibility in the ABC transporter MsbA: Alternating access with a twist

ATP-binding cassette (ABC) transporters are integral membrane proteins that translocate a wide variety of substrates across cellular membranes and are conserved from bacteria to humans. Here we compare four x-ray structures of the bacterial ABC lipid flippase, MsbA, trapped in different conformation...

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Detalhes bibliográficos
Main Authors: Ward, Andrew, Reyes, Christopher L., Yu, Jodie, Roth, Christopher B., Chang, Geoffrey
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2141898/
https://ncbi.nlm.nih.gov/pubmed/18024585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709388104
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