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Asymmetry in the Homodimeric ABC Transporter MsbA Recognized by a DARPin

ABC transporters harness the energy from ATP binding and hydrolysis to translocate substrates across the membrane. Binding of two ATP molecules at the nucleotide binding domains (NBDs) leads to the formation of an outward-facing state. The conformational changes required to reset the transporter to...

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Hlavní autoři: Mittal, Anshumali, Böhm, Simon, Grütter, Markus G., Bordignon, Enrica, Seeger, Markus A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370220/
https://ncbi.nlm.nih.gov/pubmed/22523072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.359794
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