Effects of apolipoprotein B on lifespan and risks of major diseases including type 2 diabetes: a mendelian randomisation analysis using outcomes in first-degree relatives

BACKGROUND: Apolipoprotein B (apoB) is emerging as the crucial lipoprotein trait for the role of lipoprotein lipids in the aetiology of coronary heart disease. In this study, we evaluated the effects of genetically predicted apoB on outcomes in first-degree relatives. METHODS: Data on lipoprotein li...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Lancet Healthy Longev
Päätekijät: Richardson, Tom G, Wang, Qin, Sanderson, Eleanor, Mahajan, Anubha, McCarthy, Mark I, Frayling, Timothy M, Ala-Korpela, Mika, Sniderman, Allan, Smith, George Davey, Holmes, Michael V
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2021
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611924/
https://ncbi.nlm.nih.gov/pubmed/34729547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2666-7568(21)00086-6
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