Effects of apolipoprotein B on lifespan and risks of major diseases including type 2 diabetes: a mendelian randomisation analysis using outcomes in first-degree relatives

BACKGROUND: Apolipoprotein B (apoB) is emerging as the crucial lipoprotein trait for the role of lipoprotein lipids in the aetiology of coronary heart disease. In this study, we evaluated the effects of genetically predicted apoB on outcomes in first-degree relatives. METHODS: Data on lipoprotein li...

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Detalhes bibliográficos
Publicado no:Lancet Healthy Longev
Main Authors: Richardson, Tom G, Wang, Qin, Sanderson, Eleanor, Mahajan, Anubha, McCarthy, Mark I, Frayling, Timothy M, Ala-Korpela, Mika, Sniderman, Allan, Smith, George Davey, Holmes, Michael V
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611924/
https://ncbi.nlm.nih.gov/pubmed/34729547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2666-7568(21)00086-6
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