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Multivariable Mendelian Randomization and Mediation
Mendelian randomization (MR) is the use of genetic variants associated with an exposure to estimate the causal effect of that exposure on an outcome. Mediation analysis is the method of decomposing the effects of an exposure on an outcome, which act directly, and those that act via mediating variabl...
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| Udgivet i: | Cold Spring Harb Perspect Med |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7849347/ https://ncbi.nlm.nih.gov/pubmed/32341063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a038984 |
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