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Multivariable Mendelian Randomization and Mediation

Mendelian randomization (MR) is the use of genetic variants associated with an exposure to estimate the causal effect of that exposure on an outcome. Mediation analysis is the method of decomposing the effects of an exposure on an outcome, which act directly, and those that act via mediating variabl...

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Pubblicato in:Cold Spring Harb Perspect Med
Autore principale: Sanderson, Eleanor
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849347/
https://ncbi.nlm.nih.gov/pubmed/32341063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a038984
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