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Multivariable Mendelian Randomization and Mediation

Mendelian randomization (MR) is the use of genetic variants associated with an exposure to estimate the causal effect of that exposure on an outcome. Mediation analysis is the method of decomposing the effects of an exposure on an outcome, which act directly, and those that act via mediating variabl...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Med
Autor principal: Sanderson, Eleanor
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849347/
https://ncbi.nlm.nih.gov/pubmed/32341063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a038984
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