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An examination of multivariable Mendelian randomization in the single-sample and two-sample summary data settings

BACKGROUND: Mendelian randomization (MR) is a powerful tool in epidemiology that can be used to estimate the causal effect of an exposure on an outcome in the presence of unobserved confounding, by utilizing genetic variants that are instrumental variables (IVs) for the exposure. This has been exten...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Epidemiol
Prif Awduron: Sanderson, Eleanor, Davey Smith, George, Windmeijer, Frank, Bowden, Jack
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6734942/
https://ncbi.nlm.nih.gov/pubmed/30535378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyy262
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