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An examination of multivariable Mendelian randomization in the single-sample and two-sample summary data settings

BACKGROUND: Mendelian randomization (MR) is a powerful tool in epidemiology that can be used to estimate the causal effect of an exposure on an outcome in the presence of unobserved confounding, by utilizing genetic variants that are instrumental variables (IVs) for the exposure. This has been exten...

詳細記述

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書誌詳細
出版年:Int J Epidemiol
主要な著者: Sanderson, Eleanor, Davey Smith, George, Windmeijer, Frank, Bowden, Jack
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6734942/
https://ncbi.nlm.nih.gov/pubmed/30535378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyy262
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