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Pleiotropy robust methods for multivariable Mendelian randomization
Mendelian randomization is a powerful tool for inferring the presence, or otherwise, of causal effects from observational data. However, the nature of genetic variants is such that pleiotropy remains a barrier to valid causal effect estimation. There are many options in the literature for pleiotropy...
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| Publicado no: | Stat Med |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7612169/ https://ncbi.nlm.nih.gov/pubmed/34342032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.9156 |
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