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Extending the MR‐Egger method for multivariable Mendelian randomization to correct for both measured and unmeasured pleiotropy

Methods have been developed for Mendelian randomization that can obtain consistent causal estimates while relaxing the instrumental variable assumptions. These include multivariable Mendelian randomization, in which a genetic variant may be associated with multiple risk factors so long as any associ...

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Detalhes bibliográficos
Publicado no:Stat Med
Main Authors: Rees, Jessica M. B., Wood, Angela M., Burgess, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725762/
https://ncbi.nlm.nih.gov/pubmed/28960498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.7492
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