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Target-gene independent functions of MYC oncogenes

Oncoproteins of the MYC family are major drivers of human tumorigenesis. Since a large body of evidence indicates that MYC proteins are transcription factors, studying their function has focused on the biology of the downstream target genes. Detailed studies of MYC-dependent changes in RNA levels ha...

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Pubblicato in:Nat Rev Mol Cell Biol
Autori principali: Baluapuri, Apoorva, Wolf, Elmar, Eilers, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611238/
https://ncbi.nlm.nih.gov/pubmed/32071436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41580-020-0215-2
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