A mutant O-GlcNAcase enriches Drosophila developmental regulators

Protein O-GlcNAcylation is a reversible post-translational modification of serines/threonines on nucleocytoplasmic proteins. It is cycled by the enzymes O-GlcNAc transferase (OGT) and O-GlcNAc hydrolase (O-GlcNAcase or OGA). Genetic approaches in model organisms have revealed that protein O-GlcNAcyl...

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Bibliographic Details
Published in:Nat Chem Biol
Main Authors: Selvan, Nithya, Williamson, Ritchie, Mariappa, Daniel, Campbell, David G., Gourlay, Robert, Ferenbach, Andrew T., Aristotelous, Tonia, Hopkins-Navratilova, Iva, Trost, Matthias, van Aalten, Daan M. F.
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611224/
https://ncbi.nlm.nih.gov/pubmed/28604694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2404
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