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A mutant O-GlcNAcase as a probe to reveal global dynamics of the Drosophila O-GlcNAc developmental proteome

Nucleocytoplasmic protein O-GlcNAcylation is essential for embryogenesis. The dynamics of the O-GlcNAc proteome and the underlying mechanistic biology linking it to embryonic development is not understood. Harnessing the unusual properties of an O-GlcNAcase mutant that binds O-GlcNAc sites with nano...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Mariappa, Daniel, Selvan, Nithya, Borodkin, Vladimir, Alonso, Jana, Ferenbach, Andrew T., Shepherd, Claire, Navratilova, Iva Hopkins, vanAalten, Daan M. F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941924/
https://ncbi.nlm.nih.gov/pubmed/26348912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20150610
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