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O-GlcNAcase: Promiscuous Hexosaminidase or Key Regulator of O-GlcNAc Signaling?

O-GlcNAc signaling is regulated by an opposing pair of enzymes: O-GlcNAc transferase installs and O-GlcNAcase (OGA) removes the modification from proteins. The dynamics and regulation of this process are only beginning to be understood as the physiological functions of both enzymes are being probed...

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Foilsithe in:J Biol Chem
Main Authors: Alonso, Jana, Schimpl, Marianne, van Aalten, Daan M. F.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263850/
https://ncbi.nlm.nih.gov/pubmed/25336650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R114.609198
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