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Systematic refinement of gene annotations by parsing mRNA 3′ end sequencing datasets
Alternative cleavage and polyadenylation generates mRNA 3′ isoforms in a cell type-specific manner. Due to finite available RNA sequencing data of organisms with vast cell type complexity, currently available gene annotation resources are incomplete, which poses significant challenges to the compreh...
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| 發表在: | Methods Enzymol |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7611212/ https://ncbi.nlm.nih.gov/pubmed/34183122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2021.03.016 |
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