The mutational signature profile of known and suspected human carcinogens in mice

Epidemiological studies have identified many environmental agents that appear to significantly increase cancer risk in human populations. By analysis of tumour genomes from mice chronically exposed to one of 20 known or suspected human carcinogens, we reveal that most agents do not generate distinct...

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Publicat a:Nat Genet
Autors principals: Riva, Laura, Pandiri, Arun R., Li, Yun Rose, Droop, Alastair, Hewinson, James, Quail, Michael A., Iyer, Vivek, Shepherd, Rebecca, Herbert, Ronald A., Campbell, Peter J., Sills, Robert C., Alexandrov, Ludmil B., Balmain, Allan, Adams, David J.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610456/
https://ncbi.nlm.nih.gov/pubmed/32989322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-020-0692-4
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