The mutational signature profile of known and suspected human carcinogens in mice

Epidemiological studies have identified many environmental agents that appear to significantly increase cancer risk in human populations. By analysis of tumour genomes from mice chronically exposed to one of 20 known or suspected human carcinogens, we reveal that most agents do not generate distinct...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Genet
Prif Awduron: Riva, Laura, Pandiri, Arun R., Li, Yun Rose, Droop, Alastair, Hewinson, James, Quail, Michael A., Iyer, Vivek, Shepherd, Rebecca, Herbert, Ronald A., Campbell, Peter J., Sills, Robert C., Alexandrov, Ludmil B., Balmain, Allan, Adams, David J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610456/
https://ncbi.nlm.nih.gov/pubmed/32989322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-020-0692-4
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