A novel role for P2X7 receptor signalling in the survival of mouse embryonic stem cells()()

Por Thompson, Belinda A.N., Storm, Michael P., Hewinson, James, Hogg, Sarah, Welham, Melanie J., MacKenzie, Amanda B.
Publicado em 2012

Essential Role of Phox2b-Expressing Ventrolateral Brainstem Neurons in the Chemosensory Control of Inspiration and Expiration

Por Marina, Nephtali, Abdala, Ana P., Trapp, Stefan, Li, Aihua, Nattie, Eugene E., Hewinson, James, Smith, Jeffrey C., Paton, Julian F. R., Gourine, Alexander V.
Publicado em 2010

Optoactivation of Locus Ceruleus Neurons Evokes Bidirectional Changes in Thermal Nociception in Rats

Por Hickey, Louise, Li, Yong, Fyson, Sarah J., Watson, Thomas C., Perrins, Ray, Hewinson, James, Teschemacher, Anja G., Furue, Hidemasa, Lumb, Bridget M., Pickering, Anthony E.
Publicado em 2014

Evolution of metastasis revealed by mutational landscapes of chemically induced skin cancers

Por McCreery, Melissa Q, Halliwill, Kyle D, Chin, Douglas, Delrosario, Reyno, Hirst, Gillian, Vuong, Peter, Jen, Kuang-Yu, Hewinson, James, Adams, David J, Balmain, Allan
Publicado no Nat Med (2015)

Mutational analysis identifies therapeutic biomarkers in inflammatory bowel disease-associated colorectal cancers

Por Din, Shahida, Wong, Kim, Mueller, Mike F, Oniscu, Anca, Hewinson, James, Black, Catherine J, Miller, Martin L, Jiménez-Sánchez, Alejandro, Rabbie, Roy, Rashid, Mamunar, Satsangi, Jack, Adams, David J, Arends, Mark J
Publicado no Clin Cancer Res (2018)

Manipulation of dorsal raphe serotonergic neurons modulates active coping to inescapable stress and anxiety-related behaviors in mice and rats

Por Nishitani, Naoya, Nagayasu, Kazuki, Asaoka, Nozomi, Yamashiro, Mayumi, Andoh, Chihiro, Nagai, Yuma, Kinoshita, Haruko, Kawai, Hiroyuki, Shibui, Norihiro, Liu, Beihui, Hewinson, James, Shirakawa, Hisashi, Nakagawa, Takayuki, Hashimoto, Hitoshi, Kasparov, Sergey, Kaneko, Shuji
Publicado no Neuropsychopharmacology (2018)

A population-based analysis of germline BAP1 mutations in melanoma

Por O’Shea, Sally J., Robles-Espinoza, Carla Daniela, McLellan, Lauren, Harrigan, Jeanine, Jacq, Xavier, Hewinson, James, Iyer, Vivek, Merchant, Will, Elliott, Faye, Harland, Mark, Bishop, D. Timothy, Newton-Bishop, Julia A., Adams, David J.
Publicado no Hum Mol Genet (2017)

Upregulation of junctional adhesion molecule-A is a putative prognostic marker of hypertension

Por Xu, Haibo, Oliveira-Sales, Elizabeth B., McBride, Fiona, Liu, Beihui, Hewinson, James, Toward, Marie, Hendy, Emma B., Graham, Delyth, Dominiczak, Anna F., Giannotta, Monica, Waki, Hidefumi, Ascione, Raimondo, Paton, Julian F.R., Kasparov, Sergey
Publicado em 2012

The mutational signature profile of known and suspected human carcinogens in mice

Por Riva, Laura, Pandiri, Arun R., Li, Yun Rose, Droop, Alastair, Hewinson, James, Quail, Michael A., Iyer, Vivek, Shepherd, Rebecca, Herbert, Ronald A., Campbell, Peter J., Sills, Robert C., Alexandrov, Ludmil B., Balmain, Allan, Adams, David J.
Publicado no Nat Genet (2020)

Combinatorial CRISPR screen identifies fitness effects of gene paralogues

Por Thompson, Nicola A., Ranzani, Marco, van der Weyden, Louise, Iyer, Vivek, Offord, Victoria, Droop, Alastair, Behan, Fiona, Gonçalves, Emanuel, Speak, Anneliese, Iorio, Francesco, Hewinson, James, Harle, Victoria, Robertson, Holly, Anderson, Elizabeth, Fu, Beiyuan, Yang, Fengtang, Zagnoli-Vieira, Guido, Chapman, Phil, Del Castillo Velasco-Herrera, Martin, Garnett, Mathew J., Jackson, Stephen P., Adams, David J.
Publicado no Nat Commun (2021)

ALPK1 hotspot mutation as a driver of human spiradenoma and spiradenocarcinoma

Por Rashid, Mamunur, van der Horst, Michiel, Mentzel, Thomas, Butera, Francesca, Ferreira, Ingrid, Pance, Alena, Rütten, Arno, Luzar, Bostjan, Marusic, Zlatko, de Saint Aubain, Nicolas, Ko, Jennifer S., Billings, Steven D., Chen, Sofia, Abi Daoud, Marie, Hewinson, James, Louzada, Sandra, Harms, Paul W., Cerretelli, Guia, Robles-Espinoza, Carla Daniela, Patel, Rajiv M., van der Weyden, Louise, Bakal, Chris, Hornick, Jason L., Arends, Mark J., Brenn, Thomas, Adams, David J.
Publicado no Nat Commun (2019)

Association of the POT1 Germline Missense Variant p.I78T With Familial Melanoma

Por Wong, Kim, Robles-Espinoza, Carla Daniela, Rodriguez, David, Rudat, Saskia S., Puig, Susana, Potrony, Miriam, Wong, Chi C., Hewinson, James, Aguilera, Paula, Puig-Butille, Joan Anton, Bressac-de Paillerets, Brigitte, Zattara, Hélène, van der Weyden, Louise, Fletcher, Christopher D. M., Brenn, Thomas, Arends, Mark J., Quesada, Víctor, Newton-Bishop, Julia A., Lopez-Otin, Carlos, Bishop, D. Timothy, Harms, Paul W., Johnson, Timothy M., Durham, Alison B., Lombard, David B., Adams, David J.
Publicado no JAMA Dermatol (2018)