Association of the POT1 Germline Missense Variant p.I78T With Familial Melanoma

IMPORTANCE: The protection of telomeres 1 protein (POT1) is a critical component of the shelterin complex, a multiple-protein machine that regulates telomere length and protects telomere ends. Germline variants in POT1 have been linked to familial melanoma, and somatic mutations are associated with...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:JAMA Dermatol
Main Authors: Wong, Kim, Robles-Espinoza, Carla Daniela, Rodriguez, David, Rudat, Saskia S., Puig, Susana, Potrony, Miriam, Wong, Chi C., Hewinson, James, Aguilera, Paula, Puig-Butille, Joan Anton, Bressac-de Paillerets, Brigitte, Zattara, Hélène, van der Weyden, Louise, Fletcher, Christopher D. M., Brenn, Thomas, Arends, Mark J., Quesada, Víctor, Newton-Bishop, Julia A., Lopez-Otin, Carlos, Bishop, D. Timothy, Harms, Paul W., Johnson, Timothy M., Durham, Alison B., Lombard, David B., Adams, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2018
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506889/
https://ncbi.nlm.nih.gov/pubmed/30586141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamadermatol.2018.3662
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados