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Evolution of metastasis revealed by mutational landscapes of chemically induced skin cancers
Human tumors show a high level of genetic heterogeneity, but the processes that influence the timing and route of metastatic dissemination of the subclones are unknown. Here we have used whole-exome sequencing of 103 matched benign, malignant and metastatic skin tumors from genetically heterogeneous...
Tallennettuna:
| Julkaisussa: | Nat Med |
|---|---|
| Päätekijät: | , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5094808/ https://ncbi.nlm.nih.gov/pubmed/26523969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3979 |
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