Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice

Ionising radiation (IR) is a recognised carcinogen responsible for cancer development in patients previously treated using radiotherapy, and in individuals exposed as a result of accidents at nuclear energy plants. However, the mutational signatures induced by distinct types and doses of radiation a...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Rose Li, Yun, Halliwill, Kyle D., Adams, Cassandra J., Iyer, Vivek, Riva, Laura, Mamunur, Rashid, Jen, Kuang-Yu, del Rosario, Reyno, Fredlund, Erik, Hirst, Gillian, Alexandrov, Ludmil B., Adams, David, Balmain, Allan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6971050/
https://ncbi.nlm.nih.gov/pubmed/31959748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14261-4
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