The mutational signature profile of known and suspected human carcinogens in mice

Epidemiological studies have identified many environmental agents that appear to significantly increase cancer risk in human populations. By analysis of tumour genomes from mice chronically exposed to one of 20 known or suspected human carcinogens, we reveal that most agents do not generate distinct...

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Pubblicato in:Nat Genet
Autori principali: Riva, Laura, Pandiri, Arun R., Li, Yun Rose, Droop, Alastair, Hewinson, James, Quail, Michael A., Iyer, Vivek, Shepherd, Rebecca, Herbert, Ronald A., Campbell, Peter J., Sills, Robert C., Alexandrov, Ludmil B., Balmain, Allan, Adams, David J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610456/
https://ncbi.nlm.nih.gov/pubmed/32989322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-020-0692-4
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