Rapid and accurate determination of atomistic RNA dynamic ensemble models using NMR and structure prediction

Biomolecules form dynamic ensembles of many inter-converting conformations which are key for understanding how they fold and function. However, determining ensembles is challenging because the information required to specify atomic structures for thousands of conformations far exceeds that of experi...

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Publicado no:Nat Commun
Main Authors: Shi, Honglue, Rangadurai, Atul, Abou Assi, Hala, Roy, Rohit, Case, David A., Herschlag, Daniel, Yesselman, Joseph D., Al-Hashimi, Hashim M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7608651/
https://ncbi.nlm.nih.gov/pubmed/33139729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19371-y
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