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NMR chemical exchange measurements reveal that N(6)-methyladenosine slows RNA annealing

N(6)-methyladenosine (m(6)A) is an abundant epitranscriptomic modification that plays important roles in many aspects of RNA metabolism. While m(6)A is thought to mainly function by recruiting reader proteins to specific RNA sites, the modification can also reshape RNA-protein and RNA-RNA interactio...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Shi, Honglue, Liu, Bei, Nussbaumer, Felix, Rangadurai, Atul, Kreutz, Christoph, Al-Hashimi, Hashim M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7807175/
https://ncbi.nlm.nih.gov/pubmed/31826614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b10939
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