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NMR chemical exchange measurements reveal that N(6)-methyladenosine slows RNA annealing

N(6)-methyladenosine (m(6)A) is an abundant epitranscriptomic modification that plays important roles in many aspects of RNA metabolism. While m(6)A is thought to mainly function by recruiting reader proteins to specific RNA sites, the modification can also reshape RNA-protein and RNA-RNA interactio...

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Dades bibliogràfiques
Publicat a:J Am Chem Soc
Autors principals: Shi, Honglue, Liu, Bei, Nussbaumer, Felix, Rangadurai, Atul, Kreutz, Christoph, Al-Hashimi, Hashim M.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7807175/
https://ncbi.nlm.nih.gov/pubmed/31826614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b10939
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