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miR-155 promotes T reg cell development by safeguarding medullary thymic epithelial cell maturation

During thymocyte development, medullary thymic epithelial cells (mTECs) provide appropriate instructive cues in the thymic microenvironment for not only negative selection but also the generation of regulatory T (T reg) cells. Here, we identify that miR-155, a microRNA whose expression in T reg cell...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Exp Med
Egile Nagusiak: Dong, Jiayi, Warner, Lindsey M., Lin, Ling-Li, Chen, Mei-Chi, O'Connell, Ryan M., Lu, Li-Fan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Rockefeller University Press 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7608066/
https://ncbi.nlm.nih.gov/pubmed/33125052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20192423
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