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miR-155 promotes T reg cell development by safeguarding medullary thymic epithelial cell maturation

During thymocyte development, medullary thymic epithelial cells (mTECs) provide appropriate instructive cues in the thymic microenvironment for not only negative selection but also the generation of regulatory T (T reg) cells. Here, we identify that miR-155, a microRNA whose expression in T reg cell...

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Bibliographische Detailangaben
Veröffentlicht in:J Exp Med
Hauptverfasser: Dong, Jiayi, Warner, Lindsey M., Lin, Ling-Li, Chen, Mei-Chi, O'Connell, Ryan M., Lu, Li-Fan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Rockefeller University Press 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7608066/
https://ncbi.nlm.nih.gov/pubmed/33125052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20192423
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