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miR-155 promotes T reg cell development by safeguarding medullary thymic epithelial cell maturation
During thymocyte development, medullary thymic epithelial cells (mTECs) provide appropriate instructive cues in the thymic microenvironment for not only negative selection but also the generation of regulatory T (T reg) cells. Here, we identify that miR-155, a microRNA whose expression in T reg cell...
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| Publicado en: | J Exp Med |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Rockefeller University Press
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7608066/ https://ncbi.nlm.nih.gov/pubmed/33125052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20192423 |
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