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miR-155 promotes T reg cell development by safeguarding medullary thymic epithelial cell maturation
During thymocyte development, medullary thymic epithelial cells (mTECs) provide appropriate instructive cues in the thymic microenvironment for not only negative selection but also the generation of regulatory T (T reg) cells. Here, we identify that miR-155, a microRNA whose expression in T reg cell...
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| Yayımlandı: | J Exp Med |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Rockefeller University Press
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7608066/ https://ncbi.nlm.nih.gov/pubmed/33125052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20192423 |
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