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miR-155 promotes T reg cell development by safeguarding medullary thymic epithelial cell maturation
During thymocyte development, medullary thymic epithelial cells (mTECs) provide appropriate instructive cues in the thymic microenvironment for not only negative selection but also the generation of regulatory T (T reg) cells. Here, we identify that miR-155, a microRNA whose expression in T reg cell...
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| Publicado no: | J Exp Med |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7608066/ https://ncbi.nlm.nih.gov/pubmed/33125052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20192423 |
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