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miR-155 promotes T reg cell development by safeguarding medullary thymic epithelial cell maturation

During thymocyte development, medullary thymic epithelial cells (mTECs) provide appropriate instructive cues in the thymic microenvironment for not only negative selection but also the generation of regulatory T (T reg) cells. Here, we identify that miR-155, a microRNA whose expression in T reg cell...

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Detaylı Bibliyografya
Yayımlandı:J Exp Med
Asıl Yazarlar: Dong, Jiayi, Warner, Lindsey M., Lin, Ling-Li, Chen, Mei-Chi, O'Connell, Ryan M., Lu, Li-Fan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Rockefeller University Press 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7608066/
https://ncbi.nlm.nih.gov/pubmed/33125052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20192423
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