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Type I interferon signaling mediates Mycobacterium tuberculosis–induced macrophage death

Macrophages help defend the host against Mycobacterium tuberculosis (Mtb), the major cause of tuberculosis (TB). Once phagocytized, Mtb resists killing by macrophages, replicates inside them, and leads to their death, releasing Mtb that can infect other cells. We found that the death of Mtb-infected...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Exp Med
Päätekijät: Zhang, Li, Jiang, Xiuju, Pfau, Daniel, Ling, Yan, Nathan, Carl F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Rockefeller University Press 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7608065/
https://ncbi.nlm.nih.gov/pubmed/33125053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20200887
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