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Mycobacterium tuberculosis inhibits autocrine type I interferon signaling to increase intracellular survival.
The type I interferons (IFN-α and -β) are important for host defense against viral infections. In contrast, their role in defense against non-viral pathogens is more ambiguous. Here we report that IFN-β-signaling in murine bone-marrow derived macrophages has a cell intrinsic protective capacity agai...
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| Veröffentlicht in: | J Immunol |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6456408/ https://ncbi.nlm.nih.gov/pubmed/30833347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801303 |
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