MyD88 Primes Macrophages for Full-Scale Activation by Interferon-γ yet Mediates Few Responses to Mycobacterium tuberculosis

Macrophages are activated from a resting state by a combination of cytokines and microbial products. Microbes are often sensed through Toll-like receptors signaling through MyD88. We used large-scale microarrays in multiple replicate experiments followed by stringent statistical analysis to compare...

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Autors principals: Shi, Shuangping, Nathan, Carl, Schnappinger, Dirk, Drenkow, Jörg, Fuortes, Michele, Block, Ellen, Ding, Aihao, Gingeras, Thomas R., Schoolnik, Gary, Akira, Shizuo, Takeda, Kiyoshi, Ehrt, Sabine
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2003
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194223/
https://ncbi.nlm.nih.gov/pubmed/14517275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030603
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