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A 12-Lipoxygenase-Gpr31 signaling axis is required for pancreatic organogenesis in the zebrafish
12-lipoxygenase (12-LOX) is a key enzyme in arachidonic acid metabolism, and alongside its major product, 12-HETE, plays a key role in promoting inflammatory signaling during diabetes pathogenesis. Although 12-LOX is a proposed therapeutic target to protect pancreatic islets in the setting of diabet...
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| Gepubliceerd in: | FASEB J |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7606739/ https://ncbi.nlm.nih.gov/pubmed/32918516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201902308RR |
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