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Optimizing Lentiviral Vector Transduction of Hematopoietic Stem Cells for Gene Therapy
Autologous gene therapy using lentiviral vectors (LVs) holds promise for treating monogenetic blood diseases. However, clinical applications can be limited by suboptimal hematopoietic stem cell (HSC) transduction and insufficient quantities of available vector. We recently reported gene therapy for...
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| Publicado en: | Gene Ther |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7606410/ https://ncbi.nlm.nih.gov/pubmed/32341484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41434-020-0150-z |
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