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Efficient transduction of pigtailed macaque hematopoietic repopulating cells with HIV-based lentiviral vectors

Lentiviral vectors are attractive for hematopoietic stem cell (HSC) gene therapy because they do not require mitosis for nuclear entry, they efficiently transduce hematopoietic repopulating cells, and self-inactivating (SIN) designs can be produced at high titer. Experiments to evaluate HIV-derived...

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書誌詳細
主要な著者: Trobridge, Grant D., Beard, Brian C., Gooch, Christina, Wohlfahrt, Martin, Olsen, Philip, Fletcher, James, Malik, Punam, Kiem, Hans-Peter
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2424151/
https://ncbi.nlm.nih.gov/pubmed/18388180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-115022
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