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Efficient transduction of pigtailed macaque hematopoietic repopulating cells with HIV-based lentiviral vectors

Lentiviral vectors are attractive for hematopoietic stem cell (HSC) gene therapy because they do not require mitosis for nuclear entry, they efficiently transduce hematopoietic repopulating cells, and self-inactivating (SIN) designs can be produced at high titer. Experiments to evaluate HIV-derived...

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Bibliografiske detaljer
Main Authors: Trobridge, Grant D., Beard, Brian C., Gooch, Christina, Wohlfahrt, Martin, Olsen, Philip, Fletcher, James, Malik, Punam, Kiem, Hans-Peter
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2424151/
https://ncbi.nlm.nih.gov/pubmed/18388180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-115022
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