Cocal-pseudotyped Lentiviral Vectors Resist Inactivation by Human Serum and Efficiently Transduce Primate Hematopoietic Repopulating Cells

Lentiviral vectors are established as efficient and convenient vehicles for gene transfer. They are almost always pseudotyped with the envelope glycoprotein of vesicular stomatitis virus (VSV-G) due to the high titers that can be achieved, their stability, and broad tropism. We generated a novel coc...

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Detalhes bibliográficos
Main Authors: Trobridge, Grant D, Wu, Robert A, Hansen, Michael, Ironside, Christina, Watts, Korashon L, Olsen, Philip, Beard, Brian C, Kiem, Hans-Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862537/
https://ncbi.nlm.nih.gov/pubmed/19997089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.282
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