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Efficient transduction of pigtailed macaque hematopoietic repopulating cells with HIV-based lentiviral vectors
Lentiviral vectors are attractive for hematopoietic stem cell (HSC) gene therapy because they do not require mitosis for nuclear entry, they efficiently transduce hematopoietic repopulating cells, and self-inactivating (SIN) designs can be produced at high titer. Experiments to evaluate HIV-derived...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2424151/ https://ncbi.nlm.nih.gov/pubmed/18388180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-115022 |
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